Is the current model of higher education sustainable? Scalable? Equitable? Accessible? Can a pivot to an entrepreneurial university address some of the most complex challenges in higher education? Senior leaders from Babson Collaborative member institutions shared their expertise and vision on how institutions must adapt to address issues of scale, access, relevance, and impact. Topics explored included life-long and virtual learning, entrepreneurship as a life skill, and expanding the definition and role of higher education ecosystems.