David Blodgett

Assistant Professor

Academic Division: Math & Science
781-239-6423

Bio

​Dr. Blodgett joined Babson College in September of 2012 and currently teaches Biotechnology in the Math and Science Division. He received his B.A. in Chemistry and Spanish from Assumption College in 2002, his Ph.D. in Biomedical Science in 2007, and M.S. in Clinical Investigation in 2012 at the University of Massachusetts Medical School. Dr. Blodgett’s research interests center on glucose metabolism and the dysfunction caused by diabetes. In the lab, he investigates gene expression changes in alpha and beta cells from human pancreatic islets donors who do not have diabetes or have type 1 or type 2 diabetes. The goal of these studies is to identify genes that positively or negatively affect beta cell function, which could eventually become therapeutic targets. His research has been accepted for publication in peer-reviewed journals such as: Diabetes, Current Opinion in Endocrinology, Diabetes, and Obesity, Proceedings of the National Academy of Sciences, Journal of Biological Chemistry, Journal of General Physiology, and Biochemistry. Dr. Blodgett is generally interested in educating the broader community about the role of science and technology in everyone’s daily lives and looks forward to establishing a student centered research program on campus.

Academic Degrees

  • MS, UMASS Medical School
  • Ph D, Department of Biochemistry and Molecular Pharmacology, UMASS Medical School
  • BA, Assumption College

Academic Interests

Molecular Biology; Biotechnology; Genetics; Diabetes

Awards & Honors

  • 2015 - Excellence in Adjunct Teaching Award, Babson College
  • 2007 - Chancellor’s Award for Graduate School Education, University of Massachusetts Medical School
  • 2006 - GSBS Dean’s Award for Mid-Thesis Research, University of Massachusetts Medical School
  • 2006 - Gail-Patrick Innovation Grant Award, American Diabetes Association
  • 2004 - Graduate Fellowship Award Honorable Mention, National Science Foundation

Courses

Degree Courses 2016-2017

  • NST 1040: HUMAN BIOTECHNOLOGY

Degree Courses 2015-2016

  • SCN 2420: BIOTECHNOLOGY

Publications

Journal Articles

  • Babon, J.A., DeNicola, M.E., Blodgett, D.M., Crèvecoeur, I., Buttrick, T.S., Maehr, R., Bottino, R., Naji, A., Kaddis, J., Elyaman, W., others, (2016). Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nature Medicine, 22(12), 1482–1487.
  • Jurczyk, A., Nowosielska, A., Przewozniak, N., Aryee, K., DiIorio, P., Blodgett, D.M., Yang, C., Campbell-Thompson, M., Atkinson, M., Shultz, L., others, (2016). Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic $β$-cell function via glycogen synthase kinase-3$β$!!!. FASEB Journal, The, 30(2), 983–993.
  • Derr, A., Yang, C., Zilionis, R., Sergushichev, A., Blodgett, D.M., Redick, S., Bortell, R., Luban, J., Harlan, D.M., Kadener, S., others, (2016). End Sequence Analysis Toolkit (ESAT) expands the extractable information from single-cell RNA-seq data. Genome Research, 26(10), 1397–1410.
  • Blodgett, D.M., Redick, S.D., Harlan, D.M. (2016). Surprising Heterogeneity of Pancreatic Islet Cell Subsets. Cell Systems, 3(4), 330–332.
  • Blodgett, D.M., Nowosielska, A., Afik, S., Pechhold, S., Cura, A.J., Kennedy, N.J., Kim, S., Kucukural, A., Davis, R.J., Kent, S.C., Greiner, D.L., Garber, M.G., Harlan, D.M., diIorio, P. (2015). Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets. Diabetes, 64(9), 3172-81. link
  • Blodgett, D.M., Cura, A.C., Harlan, D.M. (2014). The pancreatic beta cell transcriptome and integrated-omics. Current Opinion in Endocrinology, Diabetes and Obesity, 21(2), 83-88. link
  • Shaw, S.Y., Blodgett, D.M., Ma, M.S., Westly, E.C., Clemons, P.A., Subramanian, A., Schreiber, S.L. (2011). Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes. Proc Natl Acad Sci U S A, 108(2), 492-7. link
  • Blodgett, D.M., Graybill, C., Carruthers, A. (2008). Analysis of glucose transporter topology and structural dynamics. J Biol Chem, 283(52), 36416-24. link
  • Blodgett, D.M., De Zutter, J.K., Levine, K.B., Karim, P., Carruthers, A. (2007). Structural basis of GLUT1 inhibition by cytoplasmic ATP. J Gen Physiol, 130(2), 157-68. link
  • Blodgett, D.M., Carruthers, A. (2005). Quench-flow analysis reveals multiple phases of GluT1-mediated sugar transport. Biochemistry, 44(7), 2650-60. link
  • Blodgett, D.M., Carruthers, A. (2004). Conventional transport assays underestimate sugar transport rates in human red cells. Blood Cells Mol Dis, 32(3), 401-7. link

Monographs

  • Winrich, C.D., Rodgers, V.L., Maclean, M.G., Blodgett, D.M., Schaefer, J. (2015). Science education as entrepreneurial thought and action methodology. Emerald.

Presentations

  • Molecular Profiling of Human Pancreatic Alpha and Beta Cells in Health and Disease
    Blodgett, D. Molecular Profiling of Human Pancreatic Alpha and Beta Cells in Health and Disease 16th Annual Rachmiel Levine-Arthur Riggs Diabetes Research Symposium, Long Beach, CA (2016)
  • Using a biotechnology course to increase scientific literacy and promote scientific relevancy for business students
    Blodgett, D. Using a biotechnology course to increase scientific literacy and promote scientific relevancy for business students 3rd Life Discovery – Doing Science Biology Education Conference, Baltimore, MD (2016)
  • doi:10.2337/db14-1-388
    Blodgett, D. doi:10.2337/db14-1-388 ADA 74th Scientific Sessions(2014)
  • doi:10.2337/db13-2161-2296
    Blodgett, D. doi:10.2337/db13-2161-2296 ADA 73rd Scientific Sessions(2013)

  • Blodgett, D. Beta Cell Biology Consortium(2013)

  • Blodgett, D. Beta Cell Biology Consortium(2012)