Faculty Profiles

David Blodgett

  • Assistant Professor
Academic Division: Math & Science
781-239-6423

Bio

Dr. Blodgett joined Babson College in September of 2012 and currently teaches Biotechnology in the Math and Science Division. He received his B.A. in Chemistry and Spanish from Assumption College in 2002, his Ph.D. in Biomedical Science in 2007, and M.S. in Clinical Investigation in 2012 at the University of Massachusetts Medical School. Dr. Blodgett’s research interests center on glucose metabolism and the dysfunction caused by diabetes. In the lab, he investigates gene expression changes in alpha and beta cells from human pancreatic islets donors who do not have diabetes or have type 1 or type 2 diabetes. The goal of these studies is to identify genes that positively or negatively affect beta cell function, which could eventually become therapeutic targets. His research has been accepted for publication in peer-reviewed journals such as: Diabetes, Current Opinion in Endocrinology, Diabetes, and Obesity, Proceedings of the National Academy of Sciences, Journal of Biological Chemistry, Journal of General Physiology, and Biochemistry.

Dr. Blodgett is generally interested in educating the broader community about the role of science and technology in everyone’s daily lives and looks forward to establishing a student centered research program on campus.

Academic Degrees

  • MS, UMASS Medical School
  • Ph D, Department of Biochemistry and Molecular Pharmacology, UMASS Medical School
  • BA, Assumption College

Academic Interests

Molecular Biology; Biotechnology; Genetics; Diabetes

Awards & Honors

  • 2018 — BFRF Awards for Excellence in Scholarship, Babson College
  • 2015 — Excellence in Adjunct Teaching Award, Babson College
  • 2007 — Chancellor’s Award for Graduate School Education, University of Massachusetts Medical School
  • 2006 — GSBS Dean’s Award for Mid-Thesis Research, University of Massachusetts Medical School
  • 2006 — Gail-Patrick Innovation Grant Award, American Diabetes Association
  • 2004 — Graduate Fellowship Award Honorable Mention, National Science Foundation
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Courses

  • Degree Courses 2019

    • NST 2040 CASE STUDIES IN SUSTAINABLE FOOD SYSTEMS
  • Degree Courses 2018

    • NST 2040 CASE STUDIES IN SUSTAINABLE FOOD SYSTEMS

Publications

Journal Articles

  • Brissova, M., Haliyur, R., Saunders, D., Shrestha, S., Dai, C., Blodgett, D.M., Bottino, R., Campbell-Thompson, M., Aramandla, R., Poffenberger, G., Lindner, J., Pan, F.C., von Herrath, M.G., Greiner, D.L., Shultz, L.D., Sanyoura, M., Philipson, L.H., Atkinson, M.A., Harlan, D.M., Levy, S.E., Prasad, N., Stein, R., Powers, A.C. (2018). α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes. Vol: 22, Issue: 10, Page: 2667-2676. link
  • Babon, J.A., DeNicola, M.E., Blodgett, D.M., Crèvecoeur, I., Buttrick, T.S., Maehr, R., Bottino, R., Naji, A., Kaddis, J., Elyaman, W., others, . (2016). Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nature Medicine. Vol: 22, Issue: 12, Page: 1482–1487. Nature Publishing Group.
  • Jurczyk, A., Nowosielska, A., Przewozniak, N., Aryee, K., DiIorio, P., Blodgett, D.M., Yang, C., Campbell-Thompson, M., Atkinson, M., Shultz, L., others, . (2016). Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic $β$-cell function via glycogen synthase kinase-3$β$!!!. FASEB Journal, The. Vol: 30, Issue: 2, Page: 983–993. Federation of American Societies for Experimental Biology.
  • Derr, A., Yang, C., Zilionis, R., Sergushichev, A., Blodgett, D.M., Redick, S., Bortell, R., Luban, J., Harlan, D.M., Kadener, S., others, . (2016). End Sequence Analysis Toolkit (ESAT) expands the extractable information from single-cell RNA-seq data. Genome Research. Vol: 26, Issue: 10, Page: 1397–1410. Cold Spring Harbor Laboratory Press.
  • Blodgett, D.M., Redick, S.D., Harlan, D.M. (2016). Surprising Heterogeneity of Pancreatic Islet Cell Subsets. Cell Systems. Vol: 3, Issue: 4, Page: 330–332. Cell Press.
  • Blodgett, D.M., Nowosielska, A., Afik, S., Pechhold, S., Cura, A.J., Kennedy, N.J., Kim, S., Kucukural, A., Davis, R.J., Kent, S.C., Greiner, D.L., Garber, M.G., Harlan, D.M., diIorio, P. (2015). Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets. Diabetes. Vol: 64, Issue: 9, Page: 3172-81. American Diabetes Association. link
  • Blodgett, D.M., Cura, A.C., Harlan, D.M. (2014). The pancreatic beta cell transcriptome and integrated-omics. Current Opinion in Endocrinology, Diabetes and Obesity. Vol: 21, Issue: 2, Page: 83-88. Lippincott Williams & Wilkins, Ltd.. link
  • Shaw, S.Y., Blodgett, D.M., Ma, M.S., Westly, E.C., Clemons, P.A., Subramanian, A., Schreiber, S.L. (2011). Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes. Proc Natl Acad Sci U S A. Vol: 108, Issue: 2, Page: 492-7. link
  • Blodgett, D.M., Graybill, C., Carruthers, A. (2008). Analysis of glucose transporter topology and structural dynamics. J Biol Chem. Vol: 283, Issue: 52, Page: 36416-24. link
  • Blodgett, D.M., De Zutter, J.K., Levine, K.B., Karim, P., Carruthers, A. (2007). Structural basis of GLUT1 inhibition by cytoplasmic ATP. J Gen Physiol. Vol: 130, Issue: 2, Page: 157-68. link
  • Blodgett, D.M., Carruthers, A. (2005). Quench-flow analysis reveals multiple phases of GluT1-mediated sugar transport. Biochemistry. Vol: 44, Issue: 7, Page: 2650-60. link
  • Blodgett, D.M., Carruthers, A. (2004). Conventional transport assays underestimate sugar transport rates in human red cells. Blood Cells Mol Dis. Vol: 32, Issue: 3, Page: 401-7. link

Books

  • Winrich, C.D., Rodgers, V.L., Maclean, M.G., Blodgett, D.M., Schaefer, J. (2015). Science education as entrepreneurial thought and action methodology: Evolving Entrepreneurial Education: Innovation in the Babson Classroom. Emerald.

Presentations

  • Lessons from Islet Cell Transcriptomes: the illustration of heterogeneity in T1D beta cells Blodgett, D. 2018 nPOD (The Network for Pancreatic Organ Donors with Diabetes) Annual Meeting, Hollywood Florida (2018)
  • Type I Diabetes - Immune Genes in Target Cells Blodgett, D. Babson Research Day, Babson College (2018)
  • How does diabetes affect human pancreas genetics and how do we study it? Blodgett, D. Babson Research Day, Babson College (2017)
  • Molecular Profiling of Human Pancreatic Alpha and Beta Cells in Health and Disease Blodgett, D. 16th Annual Rachmiel Levine-Arthur Riggs Diabetes Research Symposium, Long Beach, CA (2016)
  • Using a biotechnology course to increase scientific literacy and promote scientific relevancy for business students Blodgett, D. 3rd Life Discovery – Doing Science Biology Education Conference, Baltimore, MD (2016)
  • doi:10.2337/db14-1-388 Blodgett, D. ADA 74th Scientific Sessions, (2014)
  • doi:10.2337/db13-2161-2296 Blodgett, D. ADA 73rd Scientific Sessions, (2013)
  • Blodgett, D. Beta Cell Biology Consortium, (2013)
  • Blodgett, D. Beta Cell Biology Consortium, (2012)
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